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Polychromatic phase-contrast bright-field x-ray scattering (PPBCBS) is used to obtain simultaneously the coherent and elastic intensities of a sample as a function of wavelength, which is useful for several scattering-based investigations. This proof-of-principle work demonstrates the PPBCBS method through the evaluation of the elastic properties of a single spherical scatterer and the simultaneous investigation of a titania solid, enabling the determination of the elasticity and refractive index of anatase titania.Convenience stores earn $9 billion a year in Canada
TORONTO, July 3, 2012 /CNW/ –
The convenience store industry in Canada earned $9 billion last year – not including the sale of alcohol – according to a new research report from IRI Canada. The convenience store industry also generated almost a million jobs across the country.
The findings come as part of IRI’s (IRI) 2012 Canadian Retail Sector Report, which found that retail sales in Canada are the best in recent years, even though sales growth is expected to slow during 2012. The report also states that both convenience and mass merchants continue to do well in Canada. Convenience store sales grew by 2.3 per cent in 2011, the best growth in the history of the sector.
In 2011, almost seven million consumers visited a Canadian convenience store each day. The average transaction size in 2011 was $5.87 per visit. The largest increase in convenience store visits came in Ontario where visits jumped 3.9 per cent in 2011 compared to 2010. The largest product mix change came in Alberta where convenience store visits grew by 6.7 per cent in 2011.
Mass merchants (including gas stations, drug stores, dollar stores and grocery stores) had the highest overall sales of $196 billion in Canada in 2011 – up 3.8 per cent compared to 2010.
“Results have been good for Canadian retailers in 2011 and we expect this trend to continue in the coming year. However, retailers must continue to be responsive to changing consumer preferences,” said Dianne Eyre,
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In summary, our study suggests that vitamin D deficiency can cause impaired thymic T-cell development by blocking the maturation of thymic epithelial cells, which leads to the transformation of regulatory T cells and the acceleration of tumour development and metastasis. Future studies should focus on the upstream regulatory mechanism in the thymus that controls the maturation of thymic epithelial cells. There is no doubt that we should find new strategies to overcome vitamin D deficiency to prevent cancer. Our research will benefit from collaboration with others, and research is progressing rapidly in this field.
MATERIALS AND METHODS {#s4}
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Cells, plasmids, and antibodies {#s4_1}
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The human colorectal cancer cell line (HCT116) and the human colorectal cancer cell line (HCT8) were obtained from the American Type Culture Collection (ATCC, Manassas, VA, USA). The mouse colorectal cancer cell line (CT26) was obtained from the Chinese Academy of Sciences Cell Bank (Shanghai, China). RPMI 1640 medium, Fetal bovine serum (FBS), and Dulbecco’s Modified Eagle Medium (DMEM) were purchased from Gibco. The following antibodies were used: anti-human FOXP3 (Santa Cruz); anti-mouse CD4, CD45, CD25, CD11c, CD80, CD86, FOXP3, TCRγδ, CD3, CD8 (eBioscience); anti-human CD31 (BD); phycoerythrin (PE)- and allophycocyanin (APC)- conjugated CD3 (Beckman Coulter); and anti-phospho p38, phospho-p42/p44, phospho-JNK, and
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